5HY8
Glycation restrains allosteric transition in hemoglobin: The molecular basis of oxidative stress under hyperglycemic conditions in diabetes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, S | Hemoglobin subunit alpha | polymer | 141 | 15150.4 | 5 | UniProt (P69905) Pfam (PF00042) In PDB | Homo sapiens (Human) | Alpha-globin,Hemoglobin alpha chain |
| 2 | B, D, F, H, T | Hemoglobin subunit beta | polymer | 146 | 15890.2 | 5 | UniProt (P68871) Pfam (PF00042) In PDB | Homo sapiens (Human) | Beta-globin,Hemoglobin beta chain |
| 3 | H, S, T, A, B... | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 10 | Chemie (HEM) | |||
| 4 | G, S, T, A, B... | OXYGEN MOLECULE | non-polymer | 32.0 | 8 | Chemie (OXY) | |||
| 5 | A, C, F | beta-D-fructofuranose | non-polymer | 180.2 | 3 | Chemie (FRU) | |||
| 6 | C | alpha-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (GLC) | |||
| 7 | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 155202.8 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 7141.5 | |
| All* | Total formula weight | 162344.2 |
