5FZB
Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment 4-Pyridylthiourea (N06275b) (ligand modelled based on PANDDA event map, SGC - Diamond I04-1 fragment screening)
5FZB の概要
エントリーDOI | 10.2210/pdb5fzb/pdb |
関連するPDBエントリー | 5FYB 5FYC 5FYH 5FYI 5FYM 5FYS 5FYT 5FYU 5FYV 5FYY 5FYZ 5FZ0 5FZ1 5FZ3 5FZ4 5FZ6 5FZ7 5FZ8 5FZ9 5FZA 5FZC 5FZD 5FZE 5FZF 5FZG 5FZH 5FZI 5FZK 5FZL 5FZM 5FZO |
分子名称 | LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, DIMETHYL SULFOXIDE, ... (10 entities in total) |
機能のキーワード | oxidoreductase, jarid1b, plu1, fragment screening, structural genomics consortium, sgc, diamond i04-1, pandda |
由来する生物種 | HOMO SAPIENS (HUMAN) |
細胞内の位置 | Nucleus : Q9UGL1 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 56683.80 |
構造登録者 | Nowak, R.,Krojer, T.,Johansson, C.,Kupinska, K.,Szykowska, A.,Pearce, N.,Talon, R.,Collins, P.,Gileadi, C.,Strain-Damerell, C.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,von Delft, F.,Brennan, P.E.,Oppermann, U. (登録日: 2016-03-12, 公開日: 2016-03-30, 最終更新日: 2024-01-10) |
主引用文献 | Nowak, R.,Krojer, T.,Johansson, C.,Kupinska, K.,Szykowska, A.,Pearce, N.,Talon, R.,Collins, P.,Gileadi, C.,Strain-Damerell, C.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,von Delft, F.,Brennan, P.E.,Oppermann, U. Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with Maybridge Fragment 4-Pyridylthiourea (N06275B) (Ligand Modelled Based on Pandda Event Map, Sgc -Diamond I04-1 Fragment Screening) To be Published, |
実験手法 | X-RAY DIFFRACTION (2.18 Å) |
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