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5FYT

Crystal structure of the catalytic domain of human JARID1B in complex with 3D fragment (5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl)acetic acid (N09996a)

Summary for 5FYT
Entry DOI10.2210/pdb5fyt/pdb
Related5FXV 5FXW 5FXX 5FXZ 5FY0 5FY1 5FY4 5FY5 5FY7 5FY8 5FY9 5FYB 5FYC 5FYH 5FYI 5FYM 5FYS 5FYU 5FYV 5FYY 5FYZ 5FZ0 5FZ1 5FZ3 5FZ4 5FZ6 5FZ7 5FZ8 5FZ9 5FZA 5FZB 5FZC 5FZD 5FZE 5FZF 5FZG 5FZH 5FZI 5FZK 5FZL 5FZM
DescriptorLYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ... (9 entities in total)
Functional Keywordsoxidoreductase, jarid1b, plu1, pandda, fragment soaking, x-ray fragment screening, structural genomics consortium, sgc
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus : Q9UGL1
Total number of polymer chains1
Total formula weight57091.27
Authors
Primary citationNowak, R.,Krojer, T.,Johansson, C.,Gileadi, C.,Kupinska, K.,Strain-Damerell, C.,Szykowska, A.,von Delft, F.,Burgess-Brown, N.A.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.M.,Oppermann, U.
Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with N09996A
To be Published,
Experimental method
X-RAY DIFFRACTION (1.87 Å)
Structure validation

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PDB entries from 2024-10-30

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