5FCU

CRYSTAL STRUCTURE OF THE INNER DOMAIN OF CLADE A/E HIV-1 GP120 IN COMPLEX WITH THE ADCC-POTENT RHESUS MACAQUE ANTIBODY JR4

Summary for 5FCU

• Entry DOI: 10.2210/pdb5fcu/pdb
• Related: 4H8W 4RFE 4RFN
• Descriptor: clade A/E 93TH057 HIV-1 gp120 core, JR4 FAB HEAVY CHAIN, JR4 FAB LIGHT CHAIN, ... (7 entities in total)
• Functional Keywords: hiv-1 gp120, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 3
• Total formula weight: 66985.01

Authors

Gohain, N.,Tolbert, W.D.,Pazgier, M. (deposition date: 2015-12-15, release date: 2016-03-16, Last modification date: 2023-09-27)

• Primary citation: Tolbert, W.D.,Gohain, N.,Veillette, M.,Chapleau, J.P.,Orlandi, C.,Visciano, M.L.,Ebadi, M.,DeVico, A.L.,Fouts, T.R.,Finzi, A.,Lewis, G.K.,Pazgier, M.; Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region.; Structure, 24:697-709, 2016; PubMed: 27041594; DOI: 10.1016/j.str.2016.03.005

Experimental method

X-RAY DIFFRACTION (1.85 Å)