5FCU
CRYSTAL STRUCTURE OF THE INNER DOMAIN OF CLADE A/E HIV-1 GP120 IN COMPLEX WITH THE ADCC-POTENT RHESUS MACAQUE ANTIBODY JR4
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G | clade A/E 93TH057 HIV-1 gp120 core | polymer | 169 | 18802.3 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
| 2 | H | JR4 FAB HEAVY CHAIN | polymer | 233 | 24847.8 | 1 | Macaca mulatta (RHESUS MACAQUE) | ||
| 3 | L | JR4 FAB LIGHT CHAIN | polymer | 216 | 22719.1 | 1 | Macaca mulatta (RHESUS MACAQUE) | ||
| 4 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | L | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 6 | L | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 7 | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence modifications
G: 44 - 469 (UniProt: A0A0M3KKW9)
| PDB | External Database | Details |
|---|---|---|
| Val 42 | - | expression tag |
| Pro 43 | - | expression tag |
| Ser 470 | - | expression tag |
| Gly 471 | - | expression tag |
| Gly 472 | - | expression tag |
| Gly 473 | - | expression tag |
| Asn 474 | - | expression tag |
| Ile 475 | - | expression tag |
| Lys 476 | - | expression tag |
| Asp 477 | - | expression tag |
| Asn 478 | - | expression tag |
| Trp 479 | - | expression tag |
| Arg 480 | - | expression tag |
| Ser 481 | - | expression tag |
| Glu 482 | - | expression tag |
| Leu 483 | - | expression tag |
| Tyr 484 | - | expression tag |
| Lys 485 | - | expression tag |
| Tyr 486 | - | expression tag |
| Lys 487 | - | expression tag |
| Val 488 | - | expression tag |
| Val 489 | - | expression tag |
| Gln 490 | - | expression tag |
| Ile 491 | - | expression tag |
| Glu 492 | - | expression tag |
| Pro 493 | - | expression tag |
| Leu 494 | - | expression tag |
| Gly 495 | - | expression tag |
| Ile 496 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 66369.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 615.8 | |
| All* | Total formula weight | 66985.0 |
