5EYA
TRIM25 RING domain in complex with Ubc13-Ub conjugate
Summary for 5EYA
Entry DOI | 10.2210/pdb5eya/pdb |
Related | 4LTB |
Descriptor | Ubiquitin-conjugating enzyme E2 N, Tripartite motif-containing 25 variant, Polyubiquitin-B, ... (5 entities in total) |
Functional Keywords | complex, e3 ligase, ubiquitination, signaling protein-transferase complex, signaling protein/transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 70792.72 |
Authors | Pornillos, O.,Sanchez, J.G. (deposition date: 2015-11-24, release date: 2016-08-17, Last modification date: 2019-12-25) |
Primary citation | Sanchez, J.G.,Chiang, J.J.,Sparrer, K.M.,Alam, S.L.,Chi, M.,Roganowicz, M.D.,Sankaran, B.,Gack, M.U.,Pornillos, O. Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway. Cell Rep, 16:1315-1325, 2016 Cited by PubMed: 27425606DOI: 10.1016/j.celrep.2016.06.070 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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