5EJ9
EcMenD-ThDP-Mn2+ complex soaked with 2-ketoglutarate for 2 min and isochorismate for 13 min
Summary for 5EJ9
Entry DOI | 10.2210/pdb5ej9/pdb |
Related | 5EJ4 5EJ5 5EJ6 5EJ7 5EJ8 5EJA 5EJM |
Descriptor | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, THIAMINE DIPHOSPHATE, MANGANESE (II) ION, ... (6 entities in total) |
Functional Keywords | post-decarboxylation intermediate, transferase |
Biological source | Escherichia coli K12 |
Total number of polymer chains | 8 |
Total formula weight | 496417.22 |
Authors | Song, H.G.,Dong, C.,Chen, Y.Z.,Sun, Y.R.,Guo, Z.H. (deposition date: 2015-11-01, release date: 2016-06-01, Last modification date: 2023-11-08) |
Primary citation | Song, H.G.,Dong, C.,Qin, M.M.,Chen, Y.Z.,Sun, Y.R.,Liu, J.J.,Chan, W.,Guo, Z.H. A Thiamine-Dependent Enzyme Utilizes an Active Tetrahedral Intermediate in Vitamin K Biosynthesis J.Am.Chem.Soc., 138:7244-7247, 2016 Cited by PubMed: 27213829DOI: 10.1021/jacs.6b03437 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.72 Å) |
Structure validation
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