Crystal structure of prothrombin deletion mutant residues 154-167 ( Form I )

Summary for 5EDM

DescriptorProthrombin, MAGNESIUM ION, N-ACETYL-D-GLUCOSAMINE, ... (6 entities in total)
Functional Keywordsprothrombin, kringle, protease, coagulation factor, enzyme mechanism, kinetics, structure-function, hydrolase
Biological sourceHomo sapiens (Human)
Cellular locationSecreted, extracellular space P00734
Total number of polymer chains1
Total molecular weight67047.71
Pozzi, N.,Chen, Z.,Di Cera, E. (deposition date: 2015-10-21, release date: 2016-01-20, Last modification date: 2017-09-06)
Primary citation
Pozzi, N.,Chen, Z.,Di Cera, E.
How the Linker Connecting the Two Kringles Influences Activation and Conformational Plasticity of Prothrombin.
J.Biol.Chem., 291:6071-6082, 2016
PubMed: 26763231 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M115.700401
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23830.6%4.5%7.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution