5EDD
Crystal structure of Mycobacterium tuberculosis dUTPase R140K, H145W mutant
Summary for 5EDD
Entry DOI | 10.2210/pdb5edd/pdb |
Related | 2PY4 3H6D 3HZA 3I93 3LOJ 4GCY |
Descriptor | Deoxyuridine 5'-triphosphate nucleotidohydrolase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | jelly-roll, enzyme-ligand complex, hydrolase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 18625.97 |
Authors | Nagy, G.N.,Leveles, I.,Lopata, A.,Harmat, V.,Toth, J.,Vertessy, G.B. (deposition date: 2015-10-21, release date: 2016-11-02, Last modification date: 2024-01-10) |
Primary citation | Nagy, G.N.,Suardiaz, R.,Lopata, A.,Ozohanics, O.,Vekey, K.,Brooks, B.R.,Leveles, I.,Toth, J.,Vertessy, B.G.,Rosta, E. Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases. J. Am. Chem. Soc., 138:15035-15045, 2016 Cited by PubMed: 27740761DOI: 10.1021/jacs.6b09012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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