5E2Q

Structure of human DPP3 in complex with angiotensin-II

Summary for 5E2Q

• Entry DOI: 10.2210/pdb5e2q/pdb
• Related: 3FVY 3T6B
• Descriptor: Dipeptidyl peptidase 3, angiotensin-II, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: complex, peptidase, zinc-hydrolase, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm, cytosol : Q9NY33; Secreted: P01019
• Total number of polymer chains: 2
• Total formula weight: 82660.29

Authors

Kumar, P.,Reisinger, M.,Reithofer, V.,Gruber, K. (deposition date: 2015-10-01, release date: 2016-04-13, Last modification date: 2024-01-10)

• Primary citation: Kumar, P.,Reithofer, V.,Reisinger, M.,Wallner, S.,Pavkov-Keller, T.,Macheroux, P.,Gruber, K.; Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition.; Sci Rep, 6:23787-23787, 2016; PubMed: 27025154; DOI: 10.1038/srep23787

Experimental method

X-RAY DIFFRACTION (2.404 Å)