5E2Q
Structure of human DPP3 in complex with angiotensin-II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dipeptidyl peptidase 3 | polymer | 726 | 81548.7 | 1 | UniProt (Q9NY33) Pfam (PF03571) | Homo sapiens (Human) | Dipeptidyl aminopeptidase III,Dipeptidyl arylamidase III,Dipeptidyl peptidase III,DPP III,Enkephalinase B |
| 2 | B (B) | angiotensin-II | polymer | 8 | 1048.2 | 1 | UniProt (P01019) | Homo sapiens | Serpin A8 |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D (A) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A: 1 - 726 (UniProt: Q9NY33)
| PDB | External Database | Details |
|---|---|---|
| Ser 19 | Cys 19 | engineered mutation |
| Cys 207 | Glu 207 | engineered mutation |
| Ala 451 | Glu 451 | engineered mutation |
| Cys 491 | Ser 491 | engineered mutation |
| Ser 519 | Cys 519 | engineered mutation |
| Ser 654 | Cys 654 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82596.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 63.4 | |
| All* | Total formula weight | 82660.3 |
