5E2Q
Structure of human DPP3 in complex with angiotensin-II
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0008235 | molecular_function | metalloexopeptidase activity |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008239 | molecular_function | dipeptidyl-peptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0030163 | biological_process | protein catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 801 |
| Chain | Residue |
| A | GLY162 |
| A | GLY164 |
| A | GLY167 |
| A | HOH958 |
| A | HOH1028 |
| A | HOH1037 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue K A 802 |
| Chain | Residue |
| A | SER504 |
| A | SER317 |
| A | GLY323 |
| A | ASP496 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:3934016 |
| Chain | Residue | Details |
| B | ILE5 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22493238, ECO:0007744|PDB:3FVY |
| Chain | Residue | Details |
| A | HIS450 | |
| A | HIS455 | |
| A | GLU508 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| A | ALA2 |
