5E0U
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
Summary for 5E0U
Entry DOI | 10.2210/pdb5e0u/pdb |
Related | 1AXC 5E0T 5E0V |
Descriptor | Proliferating cell nuclear antigen, Cyclin-dependent kinase inhibitor 1 (3 entities in total) |
Functional Keywords | dna replication, sliding clamp, dna binding protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : P12004 Cytoplasm: P38936 |
Total number of polymer chains | 6 |
Total formula weight | 95112.62 |
Authors | Duffy, C.M.,Hilbert, B.J.,Kelch, B.A. (deposition date: 2015-09-29, release date: 2016-04-20, Last modification date: 2023-09-27) |
Primary citation | Duffy, C.M.,Hilbert, B.J.,Kelch, B.A. A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site. J.Mol.Biol., 428:1023-1040, 2016 Cited by PubMed: 26688547DOI: 10.1016/j.jmb.2015.11.029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
Download full validation report