5CKX

Non-covalent complex of DAHP synthase and chorismate mutase from Mycobacterium tuberculosis with bound transition state analog and feedback effectors tyrosine and phenylalanine

Summary for 5CKX

Entry DOI	10.2210/pdb5ckx/pdb
Descriptor	Phospho-2-dehydro-3-deoxyheptonate aldolase AroG, Intracellular chorismate mutase, MANGANESE (II) ION, ... (10 entities in total)
Functional Keywords	protein complex, shikimate pathway, dahp-synthase, chorismate mutase, transferase-isomerase complex, transferase/isomerase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) More
Cellular location	Cytoplasm : P9WIC1
Total number of polymer chains	4
Total formula weight	126411.89
Authors	Munack, S.,Okvist, M.,Krengel, U. (deposition date: 2015-07-15, release date: 2016-03-16, Last modification date: 2024-01-10)
Primary citation	Munack, S.,Roderer, K.,Okvist, M.,Kamarauskaite, J.,Sasso, S.,van Eerde, A.,Kast, P.,Krengel, U. Remote Control by Inter-Enzyme Allostery: A Novel Paradigm for Regulation of the Shikimate Pathway. J.Mol.Biol., 428:1237-1255, 2016 Cited by PubMed: 26776476 DOI: 10.1016/j.jmb.2016.01.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation