5Y3M
Crystal structure of bovine TLR9 in complex with two DNAs (CpG DNA and TCGTTT DNA)
Summary for 5Y3M
Entry DOI | 10.2210/pdb5y3m/pdb |
Descriptor | Toll-like receptor 9, DNA (5'-D(*TP*CP*GP*T)-3'), DNA (5'-D(P*GP*GP*CP*GP*TP*T)-3'), ... (5 entities in total) |
Functional Keywords | innate immunity, toll-like receptor, leucine-rich repeat, dna binding, immune system |
Biological source | Bos taurus (Bovine) More |
Total number of polymer chains | 6 |
Total formula weight | 190571.57 |
Authors | Ohto, U.,Shimizu, T. (deposition date: 2017-07-29, release date: 2018-04-18, Last modification date: 2023-11-22) |
Primary citation | Ohto, U.,Ishida, H.,Shibata, T.,Sato, R.,Miyake, K.,Shimizu, T. Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation Immunity, 48:649-658.e4, 2018 Cited by PubMed: 29625894DOI: 10.1016/j.immuni.2018.03.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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