5VQF
Crystal Structure of pro-TGF-beta 1
Summary for 5VQF
Entry DOI | 10.2210/pdb5vqf/pdb |
Descriptor | Transforming growth factor beta-1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | pro-complex, latency, homodimer, protein binding |
Biological source | Sus scrofa (Pig) |
Total number of polymer chains | 4 |
Total formula weight | 167164.98 |
Authors | Zhao, B.,Xu, S.,Dong, X.,Lu, C.,Springer, T.A. (deposition date: 2017-05-08, release date: 2017-11-15, Last modification date: 2023-10-04) |
Primary citation | Zhao, B.,Xu, S.,Dong, X.,Lu, C.,Springer, T.A. Prodomain-growth factor swapping in the structure of pro-TGF-beta 1. J. Biol. Chem., 293:1579-1589, 2018 Cited by PubMed: 29109152DOI: 10.1074/jbc.M117.809657 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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