5VQF
Crystal Structure of pro-TGF-beta 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Transforming growth factor beta-1 | polymer | 363 | 41432.4 | 4 | UniProt (P07200) Pfam (PF00688) Pfam (PF00019) In PDB | Sus scrofa (Pig) | TGF-beta-1 |
| 2 | E | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 3 | F, G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
A, B, C, D: 1 - 361 (UniProt: P07200)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Ser 4 | Cys 33 | engineered mutation |
| Val 85 | Leu 114 | variant |
| Gln 147 | Asn 176 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 165729.6 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1435.3 | |
| All* | Total formula weight | 167165.0 |
