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5VQF

Crystal Structure of pro-TGF-beta 1

Replaces:  3RJR
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transforming growth factor beta-1polymer36341432.44UniProt (P07200)
Pfam (PF00688)
Pfam (PF00019)
Sus scrofa (Pig)TGF-beta-1
2E
(E)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched586.51In PDB
GlyTouCan (G15407YE)
3F, G
(F, G)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.42In PDB
GlyTouCan (G42666HT)
Sequence modifications
A, B, C, D: 1 - 361 (UniProt: P07200)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Ser 4Cys 33engineered mutation
Val 85Leu 114variant
Gln 147Asn 176engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight165729.6
BranchedNumber of molecules3
Total formula weight1435.3
All*Total formula weight167165.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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