5V39
Crystal structure of human vitamin D receptor ligand binding domain in complex with a VDRM
Summary for 5V39
Entry DOI | 10.2210/pdb5v39/pdb |
Descriptor | Vitamin D3 receptor, 5-(3-{4-[(2S)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl}pentan-3-yl)-3-methyl-N-(1H-tetrazol-5-yl)thiophene-2-carboxamide (3 entities in total) |
Functional Keywords | vdr, lbd, vdrm, protein binding |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29645.33 |
Authors | Wang, Y.,Pelletier, L. (deposition date: 2017-03-06, release date: 2018-03-14, Last modification date: 2024-03-06) |
Primary citation | Zheng, J.,Chang, M.R.,Stites, R.E.,Wang, Y.,Bruning, J.B.,Pascal, B.D.,Novick, S.J.,Garcia-Ordonez, R.D.,Stayrook, K.R.,Chalmers, M.J.,Dodge, J.A.,Griffin, P.R. HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions. Nat Commun, 8:923-923, 2017 Cited by PubMed: 29030554DOI: 10.1038/s41467-017-00978-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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