5V39
Crystal structure of human vitamin D receptor ligand binding domain in complex with a VDRM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Vitamin D3 receptor | polymer | 257 | 29159.7 | 1 | UniProt (P11473) Pfam (PF00104) In PDB | Homo sapiens (Human) | VDR,1,25-dihydroxyvitamin D3 receptor,Nuclear receptor subfamily 1 group I member 1 |
| 2 | A | 5-(3-{4-[(2S)-2-hydroxy-3,3-dimethylbutoxy]-3-methylphenyl}pentan-3-yl)-3-methyl-N-(1H-tetrazol-5-yl)thiophene-2-carboxamide | non-polymer | 485.6 | 1 | Chemie (8VM) | |||
| 3 | water | water | 18.0 | 87 | Chemie (HOH) |
Sequence modifications
A: 119 - 425 (UniProt: P11473)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 215 | deletion |
| - | His 216 | deletion |
| - | Pro 217 | deletion |
| - | Ser 218 | deletion |
| - | Arg 219 | deletion |
| - | Pro 220 | deletion |
| - | Asn 221 | deletion |
| - | Ser 222 | deletion |
| - | Arg 223 | deletion |
| - | His 224 | deletion |
| - | Thr 225 | deletion |
| - | Pro 226 | deletion |
| - | Ser 227 | deletion |
| - | Phe 228 | deletion |
| - | Ser 229 | deletion |
| - | Gly 230 | deletion |
| - | Asp 231 | deletion |
| - | Ser 232 | deletion |
| - | Ser 233 | deletion |
| - | Ser 234 | deletion |
| - | Ser 235 | deletion |
| - | Cys 236 | deletion |
| - | Ser 237 | deletion |
| - | Asp 238 | deletion |
| - | His 239 | deletion |
| - | Cys 240 | deletion |
| - | Ile 241 | deletion |
| - | Thr 242 | deletion |
| - | Ser 243 | deletion |
| - | Ser 244 | deletion |
| - | Asp 245 | deletion |
| - | Met 246 | deletion |
| - | Met 247 | deletion |
| - | Asp 248 | deletion |
| - | Ser 249 | deletion |
| - | Ser 250 | deletion |
| - | Ser 251 | deletion |
| - | Phe 252 | deletion |
| - | Ser 253 | deletion |
| - | Asn 254 | deletion |
| - | Leu 255 | deletion |
| - | Asp 256 | deletion |
| - | Leu 257 | deletion |
| - | Ser 258 | deletion |
| - | Glu 259 | deletion |
| - | Glu 260 | deletion |
| - | Asp 261 | deletion |
| - | Ser 262 | deletion |
| - | Asp 263 | deletion |
| - | Asp 264 | deletion |
| - | Pro 265 | deletion |
| Leu 222 | Ser 272 | conflict |
| Gly 426 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29159.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 485.6 | |
| All* | Total formula weight | 29645.3 |
