5NG9
Crystal structure of the GluA2 ligand-binding domain (S1S2J) in complex with agonist CIP-AS at 1.15 A resolution.
Summary for 5NG9
Entry DOI | 10.2210/pdb5ng9/pdb |
Descriptor | Glutamate receptor 2, CITRATE ANION, LITHIUM ION, ... (8 entities in total) |
Functional Keywords | ionotropic glutamate receptor, ampa receptor, ligand-binding domain, glua2, glur2, agonist, membrane protein |
Biological source | Rattus norvegicus (Norway Rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 1 |
Total formula weight | 30447.45 |
Authors | Laulumaa, S.,Frydenvang, K.A.,Winther, S.,Kastrup, J.S. (deposition date: 2017-03-17, release date: 2017-07-26, Last modification date: 2024-01-17) |
Primary citation | Mllerud, S.,Pinto, A.,Marconi, L.,Frydenvang, K.,Thorsen, T.S.,Laulumaa, S.,Venskutonyte, R.,Winther, S.,Moral, A.M.C.,Tamborini, L.,Conti, P.,Pickering, D.S.,Kastrup, J.S. Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors. ACS Chem Neurosci, 8:2056-2064, 2017 Cited by PubMed: 28691798DOI: 10.1021/acschemneuro.7b00201 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.15 Å) |
Structure validation
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