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5FP9

Crystal structure of human KDM4D in complex with 3-aminopyridine-4- carboxylic acid

Summary for 5FP9
Entry DOI10.2210/pdb5fp9/pdb
Related5FP3 5FP4 5FP7 5FP8 5FPA 5FPB
DescriptorHUMAN LYSINE-SPECIFIC DEMETHYLASE 4D JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3D, JUMONJI DOMAIN-CONTAINING PROTEIN 2D, JMJD2D, ZINC ION, COBALT (II) ION, ... (7 entities in total)
Functional Keywordsoxidoreductase, lysine specific histone demethylase, jmjd2d, kdm4d, jumonji
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus : Q6B0I6
Total number of polymer chains1
Total formula weight39577.63
Authors
Chung, C. (deposition date: 2015-11-27, release date: 2016-01-27, Last modification date: 2016-03-09)
Primary citationWestaway, S.M.,Preston, A.G.S.,Barker, M.D.,Brown, F.,Brown, J.A.,Campbell, M.,Chung, C.,Diallo, H.,Douault, C.,Drewes, G.,Eagle, R.,Gordon, L.,Haslam, C.,Hayhow, T.G.,Humphreys, P.G.,Joberty, G.,Katso, R.,Kruidenier, L.,Leveridge, M.,Liddle, J.,Mosley, J.,Muelbaier, M.,Randle, R.,Rioja, I.,Rueger, A.,Seal, G.A.,Sheppard, R.J.,Singh, O.,Taylor, J.,Thomas, P.,Thomson, D.,Wilson, D.M.,Lee, K.,Prinjha, R.K.
Cell Penetrant Inhibitors of the Kdm4 and Kdm5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-Pyridine Carboxylate Derivatives.
J.Med.Chem., 59:1357-, 2016
Cited by
PubMed: 26771107
DOI: 10.1021/ACS.JMEDCHEM.5B01537
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

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