5EBE
Structure of human sphingomyelinase phosphodiesterase like 3A (SMPDL3A) with 5' CMP
Summary for 5EBE
Entry DOI | 10.2210/pdb5ebe/pdb |
Related | 5EBB |
Descriptor | Acid sphingomyelinase-like phosphodiesterase 3a, THIOCYANATE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | calcineurin like phosphodiesterase, binuclear metallophosphodiesterase, acid sphingomyelinase like, hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted : Q92484 Q92484 |
Total number of polymer chains | 3 |
Total formula weight | 146510.98 |
Authors | Lim, S.M.,Yeung, K.,Tresaugues, L.,Teo, H.L.,Nordlund, P. (deposition date: 2015-10-19, release date: 2016-01-20, Last modification date: 2024-01-10) |
Primary citation | Lim, S.M.,Yeung, K.,Tresaugues, L.,Ling, T.H.,Nordlund, P. The structure and catalytic mechanism of human sphingomyelin phosphodiesterase like 3a - an acid sphingomyelinase homologue with a novel nucleotide hydrolase activity. Febs J., 283:1107-1123, 2016 Cited by PubMed: 26783088DOI: 10.1111/febs.13655 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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