5EBE

Structure of human sphingomyelinase phosphodiesterase like 3A (SMPDL3A) with 5' CMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Acid sphingomyelinase-like phosphodiesterase 3a	polymer	418	47597.6	1	UniProt (Q92484) Pfam (PF00149) Pfam (PF19272)	Homo sapiens (Human)	ASM-like phosphodiesterase 3a
2	B, C (B, C)	Acid sphingomyelinase-like phosphodiesterase 3a	polymer	415	47192.1	2	UniProt (Q92484) Pfam (PF00149) Pfam (PF19272)	Homo sapiens (Human)	ASM-like phosphodiesterase 3a
3	D (D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	E, F, G, H, L... (A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	11	Chemie (NAG)
5	I, J, O, P, Y... (A, B, C)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
6	AA, K (C, A)	CYTIDINE-5'-MONOPHOSPHATE	non-polymer		323.2	2	Chemie (C5P)
7	Q, R (B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL) PubChem (753)
8	S (B)	MALONATE ION	non-polymer		102.0	1	Chemie (MLI) PubChem (9084)
9	T (B)	5-O-phosphono-beta-D-ribofuranose	non-polymer		230.1	1	Chemie (RP5) PubChem (439167) PubChem (440101) PubChem (447568) PubChem (447634) PubChem (448203) PubChem (4175041) PubChem (13990819) PubChem (23422546) PubChem (24802507) PubChem (46876838) PubChem (53477706) PubChem (11401949) PubChem (168368775) PubChem (172642146) PubChem (91746440) PubChem (118070650) PubChem (124350436) PubChem (167077165) PubChem (168366045) PubChem (172641724)
10	BA, CA (C)	THIOCYANATE ION	non-polymer		58.1	2	Chemie (SCN) PubChem (9322)
11	DA, EA, FA (A, B, C)	water	water		18.0	130	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	141981.9
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	25
	Total formula weight	4104.6
All*	Total formula weight	146511.0

*Water molecules are not included.