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5C0D

HLA-A02 carrying AQWGPDPAAA

Summary for 5C0D
Entry DOI10.2210/pdb5c0d/pdb
Related3UTP 3UTQ 3UTS 3UTT 5C06 5C07 5C08 5C09 5C0A 5C0B 5C0C 5C0E 5C0F 5C0G 5C0H 5C0I 5C0J 5HYJ
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Marker peptide, ... (4 entities in total)
Functional Keywordsimmuno, hla-a02, 1e6-tcr, cross-reactivity, immune system
Biological sourceHomo sapiens (Human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted : P61769
Total number of polymer chains3
Total formula weight44813.71
Authors
Rizkallah, P.J.,Bulek, A.M.,Cole, D.K.,Sewell, A.K. (deposition date: 2015-06-12, release date: 2016-05-04, Last modification date: 2024-01-10)
Primary citationCole, D.K.,Bulek, A.M.,Dolton, G.,Schauenberg, A.J.,Szomolay, B.,Rittase, W.,Trimby, A.,Jothikumar, P.,Fuller, A.,Skowera, A.,Rossjohn, J.,Zhu, C.,Miles, J.J.,Peakman, M.,Wooldridge, L.,Rizkallah, P.J.,Sewell, A.K.
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126:2191-2204, 2016
Cited by
PubMed: 27183389
DOI: 10.1172/JCI85679
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.68 Å)
Structure validation

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