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5HYJ

1E6 TCR in Complex with HLA-A02 carrying AQWGPDPAAA

Summary for 5HYJ
Entry DOI10.2210/pdb5hyj/pdb
Related5C07 5C08 5C09 5C0A 5C0B 5C0C 5C0D 5C0E 5C0F 5C0G 5C0H 5C0I 5C0J
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ALA-GLN-TRP-GLY-PRO-ASP-PRO-ALA-ALA-ALA, ... (6 entities in total)
Functional Keywordsimmuno, hla-a02, 1e6-tcr, cross-reactivity, immune system
Biological sourceHomo sapiens (Human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted : P61769
Total number of polymer chains10
Total formula weight189064.48
Authors
Rizkallah, P.J.,Bulek, A.M.,Cole, D.K.,Sewell, A.K. (deposition date: 2016-02-01, release date: 2016-05-04, Last modification date: 2024-01-10)
Primary citationStadinski, B.D.,Obst, R.,Huseby, E.S.
A "hotspot" for autoimmune T cells in type 1 diabetes.
J.Clin.Invest., 126:2040-2042, 2016
Cited by
PubMed: 27183386
DOI: 10.1172/JCI88165
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.06 Å)
Structure validation

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