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3UTQ

Human HLA-A*0201-ALWGPDPAAA

Summary for 3UTQ
Entry DOI10.2210/pdb3utq/pdb
Related3UTP 3UTS 3UTT
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Insulin, ... (4 entities in total)
Functional Keywordsmajor histocompatibility complex, human leukocyte antigen, type i diabetes, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769 P01308
Total number of polymer chains3
Total formula weight44798.74
Authors
Rizkallah, P.J.,Cole, D.K.,Sewell, A.K.,Bulek, A.M. (deposition date: 2011-11-26, release date: 2012-01-25, Last modification date: 2012-03-07)
Primary citationBulek, A.M.,Cole, D.K.,Skowera, A.,Dolton, G.,Gras, S.,Madura, F.,Fuller, A.,Miles, J.J.,Gostick, E.,Price, D.A.,Drijfhout, J.W.,Knight, R.R.,Huang, G.C.,Lissin, N.,Molloy, P.E.,Wooldridge, L.,Jakobsen, B.K.,Rossjohn, J.,Peakman, M.,Rizkallah, P.J.,Sewell, A.K.
Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes.
Nat.Immunol., 13:283-289, 2012
Cited by
PubMed: 22245737
DOI: 10.1038/ni.2206
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.67 Å)
Structure validation

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