4ZUX
SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome
Summary for 4ZUX
Entry DOI | 10.2210/pdb4zux/pdb |
Descriptor | Histone H3.2, Polyubiquitin-B, SAGA-associated factor 73, ... (12 entities in total) |
Functional Keywords | dub, deubiquitinase, usp, chromatin, eraser, nucleosome, modified histone, macromolecular complex, hydrolase-dna complex, hydrolase/dna |
Biological source | Xenopus laevis (African clawed frog) More |
Cellular location | Nucleus: P84233 P53165 P62799 P06897 P02281 P50102 A6ZWK1 Ubiquitin: Cytoplasm : P0CG47 Nucleus, nucleoplasm: Q6WNK7 |
Total number of polymer chains | 40 |
Total formula weight | 784450.18 |
Authors | Morgan, M.,Wolberger, C. (deposition date: 2015-05-17, release date: 2016-02-24, Last modification date: 2016-03-09) |
Primary citation | Morgan, M.T.,Haj-Yahya, M.,Ringel, A.E.,Bandi, P.,Brik, A.,Wolberger, C. Structural basis for histone H2B deubiquitination by the SAGA DUB module. Science, 351:725-728, 2016 Cited by PubMed: 26912860DOI: 10.1126/science.aac5681 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.82 Å) |
Structure validation
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