4ZUX

SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000786	cellular_component	nucleosome
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0030527	molecular_function	structural constituent of chromatin
A	0031492	molecular_function	nucleosomal DNA binding
A	0031507	biological_process	heterochromatin formation
A	0046982	molecular_function	protein heterodimerization activity
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005694	cellular_component	chromosome
B	0006334	biological_process	nucleosome assembly
B	0030527	molecular_function	structural constituent of chromatin
B	0031507	biological_process	heterochromatin formation
B	0046982	molecular_function	protein heterodimerization activity
C	0000786	cellular_component	nucleosome
C	0003677	molecular_function	DNA binding
C	0005634	cellular_component	nucleus
C	0005694	cellular_component	chromosome
C	0030527	molecular_function	structural constituent of chromatin
C	0031507	biological_process	heterochromatin formation
C	0046982	molecular_function	protein heterodimerization activity
D	0000786	cellular_component	nucleosome
D	0002227	biological_process	innate immune response in mucosa
D	0003677	molecular_function	DNA binding
D	0005515	molecular_function	protein binding
D	0005615	cellular_component	extracellular space
D	0005634	cellular_component	nucleus
D	0005694	cellular_component	chromosome
D	0006325	biological_process	chromatin organization
D	0019731	biological_process	antibacterial humoral response
D	0030527	molecular_function	structural constituent of chromatin
D	0031507	biological_process	heterochromatin formation
D	0046982	molecular_function	protein heterodimerization activity
D	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
E	0000786	cellular_component	nucleosome
E	0003677	molecular_function	DNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005694	cellular_component	chromosome
E	0030527	molecular_function	structural constituent of chromatin
E	0031492	molecular_function	nucleosomal DNA binding
E	0031507	biological_process	heterochromatin formation
E	0046982	molecular_function	protein heterodimerization activity
F	0000786	cellular_component	nucleosome
F	0003677	molecular_function	DNA binding
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005694	cellular_component	chromosome
F	0006334	biological_process	nucleosome assembly
F	0030527	molecular_function	structural constituent of chromatin
F	0031507	biological_process	heterochromatin formation
F	0046982	molecular_function	protein heterodimerization activity
G	0000786	cellular_component	nucleosome
G	0003677	molecular_function	DNA binding
G	0005634	cellular_component	nucleus
G	0005694	cellular_component	chromosome
G	0030527	molecular_function	structural constituent of chromatin
G	0031507	biological_process	heterochromatin formation
G	0046982	molecular_function	protein heterodimerization activity
H	0000786	cellular_component	nucleosome
H	0002227	biological_process	innate immune response in mucosa
H	0003677	molecular_function	DNA binding
H	0005515	molecular_function	protein binding
H	0005615	cellular_component	extracellular space
H	0005634	cellular_component	nucleus
H	0005694	cellular_component	chromosome
H	0006325	biological_process	chromatin organization
H	0019731	biological_process	antibacterial humoral response
H	0030527	molecular_function	structural constituent of chromatin
H	0031507	biological_process	heterochromatin formation
H	0046982	molecular_function	protein heterodimerization activity
H	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
K	0000786	cellular_component	nucleosome
K	0003677	molecular_function	DNA binding
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005694	cellular_component	chromosome
K	0030527	molecular_function	structural constituent of chromatin
K	0031492	molecular_function	nucleosomal DNA binding
K	0031507	biological_process	heterochromatin formation
K	0046982	molecular_function	protein heterodimerization activity
L	0000786	cellular_component	nucleosome
L	0003677	molecular_function	DNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005694	cellular_component	chromosome
L	0006334	biological_process	nucleosome assembly
L	0030527	molecular_function	structural constituent of chromatin
L	0031507	biological_process	heterochromatin formation
L	0046982	molecular_function	protein heterodimerization activity
M	0000786	cellular_component	nucleosome
M	0003677	molecular_function	DNA binding
M	0005634	cellular_component	nucleus
M	0005694	cellular_component	chromosome
M	0030527	molecular_function	structural constituent of chromatin
M	0031507	biological_process	heterochromatin formation
M	0046982	molecular_function	protein heterodimerization activity
N	0000786	cellular_component	nucleosome
N	0002227	biological_process	innate immune response in mucosa
N	0003677	molecular_function	DNA binding
N	0005515	molecular_function	protein binding
N	0005615	cellular_component	extracellular space
N	0005634	cellular_component	nucleus
N	0005694	cellular_component	chromosome
N	0006325	biological_process	chromatin organization
N	0019731	biological_process	antibacterial humoral response
N	0030527	molecular_function	structural constituent of chromatin
N	0031507	biological_process	heterochromatin formation
N	0046982	molecular_function	protein heterodimerization activity
N	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
O	0000786	cellular_component	nucleosome
O	0003677	molecular_function	DNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005694	cellular_component	chromosome
O	0030527	molecular_function	structural constituent of chromatin
O	0031492	molecular_function	nucleosomal DNA binding
O	0031507	biological_process	heterochromatin formation
O	0046982	molecular_function	protein heterodimerization activity
P	0000786	cellular_component	nucleosome
P	0003677	molecular_function	DNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005694	cellular_component	chromosome
P	0006334	biological_process	nucleosome assembly
P	0030527	molecular_function	structural constituent of chromatin
P	0031507	biological_process	heterochromatin formation
P	0046982	molecular_function	protein heterodimerization activity
Q	0000786	cellular_component	nucleosome
Q	0003677	molecular_function	DNA binding
Q	0005634	cellular_component	nucleus
Q	0005694	cellular_component	chromosome
Q	0030527	molecular_function	structural constituent of chromatin
Q	0031507	biological_process	heterochromatin formation
Q	0046982	molecular_function	protein heterodimerization activity
R	0000786	cellular_component	nucleosome
R	0002227	biological_process	innate immune response in mucosa
R	0003677	molecular_function	DNA binding
R	0005515	molecular_function	protein binding
R	0005615	cellular_component	extracellular space
R	0005634	cellular_component	nucleus
R	0005694	cellular_component	chromosome
R	0006325	biological_process	chromatin organization
R	0019731	biological_process	antibacterial humoral response
R	0030527	molecular_function	structural constituent of chromatin
R	0031507	biological_process	heterochromatin formation
R	0046982	molecular_function	protein heterodimerization activity
R	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
U	0000124	cellular_component	SAGA complex
U	0004843	molecular_function	cysteine-type deubiquitinase activity
U	0005515	molecular_function	protein binding
U	0005634	cellular_component	nucleus
U	0006357	biological_process	regulation of transcription by RNA polymerase II
U	0006508	biological_process	proteolysis
U	0008233	molecular_function	peptidase activity
U	0008234	molecular_function	cysteine-type peptidase activity
U	0008270	molecular_function	zinc ion binding
U	0008380	biological_process	RNA splicing
U	0016579	biological_process	protein deubiquitination
U	0016787	molecular_function	hydrolase activity
U	0046695	cellular_component	SLIK (SAGA-like) complex
U	0046872	molecular_function	metal ion binding
U	0060090	molecular_function	molecular adaptor activity
U	0071819	cellular_component	DUBm complex
V	0000124	cellular_component	SAGA complex
V	0000932	cellular_component	P-body
V	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
V	0003682	molecular_function	chromatin binding
V	0003713	molecular_function	transcription coactivator activity
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005643	cellular_component	nuclear pore
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0006325	biological_process	chromatin organization
V	0006357	biological_process	regulation of transcription by RNA polymerase II
V	0006368	biological_process	transcription elongation by RNA polymerase II
V	0006406	biological_process	mRNA export from nucleus
V	0008047	molecular_function	enzyme activator activity
V	0015031	biological_process	protein transport
V	0016973	biological_process	poly(A)+ mRNA export from nucleus
V	0032880	biological_process	regulation of protein localization
V	0045893	biological_process	positive regulation of DNA-templated transcription
V	0045944	biological_process	positive regulation of transcription by RNA polymerase II
V	0046695	cellular_component	SLIK (SAGA-like) complex
V	0051028	biological_process	mRNA transport
V	0070390	cellular_component	transcription export complex 2
V	0071028	biological_process	nuclear mRNA surveillance
V	0071819	cellular_component	DUBm complex
W	0000124	cellular_component	SAGA complex
W	0003713	molecular_function	transcription coactivator activity
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0006325	biological_process	chromatin organization
W	0006357	biological_process	regulation of transcription by RNA polymerase II
W	0008047	molecular_function	enzyme activator activity
W	0008270	molecular_function	zinc ion binding
W	0045893	biological_process	positive regulation of DNA-templated transcription
W	0046695	cellular_component	SLIK (SAGA-like) complex
W	0046872	molecular_function	metal ion binding
W	0070461	cellular_component	SAGA-type complex
W	0071819	cellular_component	DUBm complex
Y	0000124	cellular_component	SAGA complex
Z	0000124	cellular_component	SAGA complex
Z	0004843	molecular_function	cysteine-type deubiquitinase activity
Z	0005515	molecular_function	protein binding
Z	0005634	cellular_component	nucleus
Z	0006357	biological_process	regulation of transcription by RNA polymerase II
Z	0006508	biological_process	proteolysis
Z	0008233	molecular_function	peptidase activity
Z	0008234	molecular_function	cysteine-type peptidase activity
Z	0008270	molecular_function	zinc ion binding
Z	0008380	biological_process	RNA splicing
Z	0016579	biological_process	protein deubiquitination
Z	0016787	molecular_function	hydrolase activity
Z	0046695	cellular_component	SLIK (SAGA-like) complex
Z	0046872	molecular_function	metal ion binding
Z	0060090	molecular_function	molecular adaptor activity
Z	0071819	cellular_component	DUBm complex
a	0000124	cellular_component	SAGA complex
a	0000932	cellular_component	P-body
a	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
a	0003682	molecular_function	chromatin binding
a	0003713	molecular_function	transcription coactivator activity
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005643	cellular_component	nuclear pore
a	0005654	cellular_component	nucleoplasm
a	0005737	cellular_component	cytoplasm
a	0006325	biological_process	chromatin organization
a	0006357	biological_process	regulation of transcription by RNA polymerase II
a	0006368	biological_process	transcription elongation by RNA polymerase II
a	0006406	biological_process	mRNA export from nucleus
a	0008047	molecular_function	enzyme activator activity
a	0015031	biological_process	protein transport
a	0016973	biological_process	poly(A)+ mRNA export from nucleus
a	0032880	biological_process	regulation of protein localization
a	0045893	biological_process	positive regulation of DNA-templated transcription
a	0045944	biological_process	positive regulation of transcription by RNA polymerase II
a	0046695	cellular_component	SLIK (SAGA-like) complex
a	0051028	biological_process	mRNA transport
a	0070390	cellular_component	transcription export complex 2
a	0071028	biological_process	nuclear mRNA surveillance
a	0071819	cellular_component	DUBm complex
b	0000124	cellular_component	SAGA complex
b	0003713	molecular_function	transcription coactivator activity
b	0005515	molecular_function	protein binding
b	0005634	cellular_component	nucleus
b	0006325	biological_process	chromatin organization
b	0006357	biological_process	regulation of transcription by RNA polymerase II
b	0008047	molecular_function	enzyme activator activity
b	0008270	molecular_function	zinc ion binding
b	0045893	biological_process	positive regulation of DNA-templated transcription
b	0046695	cellular_component	SLIK (SAGA-like) complex
b	0046872	molecular_function	metal ion binding
b	0070461	cellular_component	SAGA-type complex
b	0071819	cellular_component	DUBm complex
d	0000124	cellular_component	SAGA complex
e	0000124	cellular_component	SAGA complex
e	0004843	molecular_function	cysteine-type deubiquitinase activity
e	0005515	molecular_function	protein binding
e	0005634	cellular_component	nucleus
e	0006357	biological_process	regulation of transcription by RNA polymerase II
e	0006508	biological_process	proteolysis
e	0008233	molecular_function	peptidase activity
e	0008234	molecular_function	cysteine-type peptidase activity
e	0008270	molecular_function	zinc ion binding
e	0008380	biological_process	RNA splicing
e	0016579	biological_process	protein deubiquitination
e	0016787	molecular_function	hydrolase activity
e	0046695	cellular_component	SLIK (SAGA-like) complex
e	0046872	molecular_function	metal ion binding
e	0060090	molecular_function	molecular adaptor activity
e	0071819	cellular_component	DUBm complex
f	0000124	cellular_component	SAGA complex
f	0000932	cellular_component	P-body
f	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
f	0003682	molecular_function	chromatin binding
f	0003713	molecular_function	transcription coactivator activity
f	0005515	molecular_function	protein binding
f	0005634	cellular_component	nucleus
f	0005643	cellular_component	nuclear pore
f	0005654	cellular_component	nucleoplasm
f	0005737	cellular_component	cytoplasm
f	0006325	biological_process	chromatin organization
f	0006357	biological_process	regulation of transcription by RNA polymerase II
f	0006368	biological_process	transcription elongation by RNA polymerase II
f	0006406	biological_process	mRNA export from nucleus
f	0008047	molecular_function	enzyme activator activity
f	0015031	biological_process	protein transport
f	0016973	biological_process	poly(A)+ mRNA export from nucleus
f	0032880	biological_process	regulation of protein localization
f	0045893	biological_process	positive regulation of DNA-templated transcription
f	0045944	biological_process	positive regulation of transcription by RNA polymerase II
f	0046695	cellular_component	SLIK (SAGA-like) complex
f	0051028	biological_process	mRNA transport
f	0070390	cellular_component	transcription export complex 2
f	0071028	biological_process	nuclear mRNA surveillance
f	0071819	cellular_component	DUBm complex
g	0000124	cellular_component	SAGA complex
g	0003713	molecular_function	transcription coactivator activity
g	0005515	molecular_function	protein binding
g	0005634	cellular_component	nucleus
g	0006325	biological_process	chromatin organization
g	0006357	biological_process	regulation of transcription by RNA polymerase II
g	0008047	molecular_function	enzyme activator activity
g	0008270	molecular_function	zinc ion binding
g	0045893	biological_process	positive regulation of DNA-templated transcription
g	0046695	cellular_component	SLIK (SAGA-like) complex
g	0046872	molecular_function	metal ion binding
g	0070461	cellular_component	SAGA-type complex
g	0071819	cellular_component	DUBm complex
i	0000124	cellular_component	SAGA complex
j	0000124	cellular_component	SAGA complex
j	0004843	molecular_function	cysteine-type deubiquitinase activity
j	0005515	molecular_function	protein binding
j	0005634	cellular_component	nucleus
j	0006357	biological_process	regulation of transcription by RNA polymerase II
j	0006508	biological_process	proteolysis
j	0008233	molecular_function	peptidase activity
j	0008234	molecular_function	cysteine-type peptidase activity
j	0008270	molecular_function	zinc ion binding
j	0008380	biological_process	RNA splicing
j	0016579	biological_process	protein deubiquitination
j	0016787	molecular_function	hydrolase activity
j	0046695	cellular_component	SLIK (SAGA-like) complex
j	0046872	molecular_function	metal ion binding
j	0060090	molecular_function	molecular adaptor activity
j	0071819	cellular_component	DUBm complex
k	0000124	cellular_component	SAGA complex
k	0000932	cellular_component	P-body
k	0000973	biological_process	post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
k	0003682	molecular_function	chromatin binding
k	0003713	molecular_function	transcription coactivator activity
k	0005515	molecular_function	protein binding
k	0005634	cellular_component	nucleus
k	0005643	cellular_component	nuclear pore
k	0005654	cellular_component	nucleoplasm
k	0005737	cellular_component	cytoplasm
k	0006325	biological_process	chromatin organization
k	0006357	biological_process	regulation of transcription by RNA polymerase II
k	0006368	biological_process	transcription elongation by RNA polymerase II
k	0006406	biological_process	mRNA export from nucleus
k	0008047	molecular_function	enzyme activator activity
k	0015031	biological_process	protein transport
k	0016973	biological_process	poly(A)+ mRNA export from nucleus
k	0032880	biological_process	regulation of protein localization
k	0045893	biological_process	positive regulation of DNA-templated transcription
k	0045944	biological_process	positive regulation of transcription by RNA polymerase II
k	0046695	cellular_component	SLIK (SAGA-like) complex
k	0051028	biological_process	mRNA transport
k	0070390	cellular_component	transcription export complex 2
k	0071028	biological_process	nuclear mRNA surveillance
k	0071819	cellular_component	DUBm complex
l	0000124	cellular_component	SAGA complex
l	0003713	molecular_function	transcription coactivator activity
l	0005515	molecular_function	protein binding
l	0005634	cellular_component	nucleus
l	0006325	biological_process	chromatin organization
l	0006357	biological_process	regulation of transcription by RNA polymerase II
l	0008047	molecular_function	enzyme activator activity
l	0008270	molecular_function	zinc ion binding
l	0045893	biological_process	positive regulation of DNA-templated transcription
l	0046695	cellular_component	SLIK (SAGA-like) complex
l	0046872	molecular_function	metal ion binding
l	0070461	cellular_component	SAGA-type complex
l	0071819	cellular_component	DUBm complex
n	0000124	cellular_component	SAGA complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN U 501

Chain	Residue
U	CYS46
U	CYS49
U	CYS68
U	HIS73

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN U 502

Chain	Residue
U	CYS60
U	CYS63
U	HIS77
U	HIS83

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN U 503

Chain	Residue
U	HIS6
U	CYS96
U	CYS99
U	CYS4

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN U 504

Chain	Residue
U	HIS170
U	CYS174
U	CYS182
U	CYS185

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN U 505

Chain	Residue
U	HIS250
U	CYS271
U	CYS273
U	HIS276

---

site_id	AC6
Number of Residues	4
Details	binding site for residue ZN U 506

Chain	Residue
U	CYS289
U	CYS292
U	CYS336
U	CYS339

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN W 101

Chain	Residue
W	CYS73
W	ASN75
W	CYS76
W	CYS92

---

site_id	AC8
Number of Residues	4
Details	binding site for residue ZN Y 201

Chain	Residue
Y	CYS78
Y	CYS81
Y	HIS93
Y	CYS98

---

site_id	AC9
Number of Residues	4
Details	binding site for residue ZN Z 501

Chain	Residue
Z	CYS289
Z	GLY291
Z	CYS292
Z	CYS339

---

site_id	AD1
Number of Residues	4
Details	binding site for residue ZN Z 502

Chain	Residue
Z	CYS271
Z	GLU272
Z	CYS273
Z	HIS276

---

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN Z 503

Chain	Residue
Z	HIS170
Z	CYS174
Z	CYS182
Z	CYS185

---

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN Z 504

Chain	Residue
Z	CYS4
Z	HIS6
Z	CYS96
Z	CYS99

---

site_id	AD4
Number of Residues	4
Details	binding site for residue ZN Z 505

Chain	Residue
Z	CYS60
Z	CYS63
Z	HIS77
Z	HIS83

---

site_id	AD5
Number of Residues	5
Details	binding site for residue ZN Z 506

Chain	Residue
Z	CYS46
Z	CYS49
Z	CYS68
Z	HIS71
Z	HIS73

---

site_id	AD6
Number of Residues	5
Details	binding site for residue ZN b 101

Chain	Residue
b	CYS73
b	ASN75
b	CYS76
b	HIS88
b	CYS92

---

site_id	AD7
Number of Residues	4
Details	binding site for residue ZN d 201

Chain	Residue
d	CYS78
d	CYS81
d	HIS93
d	CYS98

---

site_id	AD8
Number of Residues	4
Details	binding site for residue ZN e 501

Chain	Residue
e	CYS46
e	CYS49
e	CYS68
e	HIS73

---

site_id	AD9
Number of Residues	4
Details	binding site for residue ZN e 502

Chain	Residue
e	CYS60
e	CYS63
e	HIS77
e	HIS83

---

site_id	AE1
Number of Residues	4
Details	binding site for residue ZN e 503

Chain	Residue
e	CYS4
e	HIS6
e	CYS96
e	CYS99

---

site_id	AE2
Number of Residues	4
Details	binding site for residue ZN e 504

Chain	Residue
e	HIS170
e	CYS174
e	CYS182
e	CYS185

---

site_id	AE3
Number of Residues	4
Details	binding site for residue ZN e 505

Chain	Residue
e	HIS250
e	CYS271
e	CYS273
e	HIS276

---

site_id	AE4
Number of Residues	6
Details	binding site for residue ZN e 506

Chain	Residue
e	CYS289
e	GLY291
e	CYS292
e	ASN295
e	CYS336
e	CYS339

---

site_id	AE5
Number of Residues	4
Details	binding site for residue ZN g 101

Chain	Residue
g	CYS73
g	CYS76
g	HIS88
g	CYS92

---

site_id	AE6
Number of Residues	4
Details	binding site for residue ZN i 201

Chain	Residue
i	CYS98
i	CYS78
i	CYS81
i	HIS93

---

site_id	AE7
Number of Residues	4
Details	binding site for residue ZN j 501

Chain	Residue
j	CYS289
j	CYS292
j	CYS336
j	CYS339

---

site_id	AE8
Number of Residues	4
Details	binding site for residue ZN j 502

Chain	Residue
j	HIS250
j	CYS271
j	CYS273
j	HIS276

---

site_id	AE9
Number of Residues	4
Details	binding site for residue ZN j 503

Chain	Residue
j	HIS170
j	CYS174
j	CYS182
j	CYS185

---

site_id	AF1
Number of Residues	4
Details	binding site for residue ZN j 504

Chain	Residue
j	CYS4
j	HIS6
j	PHE85
j	CYS96

---

site_id	AF2
Number of Residues	4
Details	binding site for residue ZN j 505

Chain	Residue
j	CYS60
j	CYS63
j	HIS77
j	HIS83

---

site_id	AF3
Number of Residues	4
Details	binding site for residue ZN j 506

Chain	Residue
j	CYS46
j	CYS49
j	CYS68
j	HIS73

---

site_id	AF4
Number of Residues	5
Details	binding site for residue ZN l 101

Chain	Residue
l	CYS73
l	ASN75
l	CYS76
l	HIS88
l	CYS92

---

site_id	AF5
Number of Residues	4
Details	binding site for residue ZN n 201

Chain	Residue
n	CYS78
n	CYS81
n	HIS93
n	CYS98

---

Functional Information from PROSITE/UniProt

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
C	ALA21-VAL27

---

site_id	PS00047
Number of Residues	5
Details	HISTONE_H4 Histone H4 signature. GAKRH

Chain	Residue	Details
B	GLY14-HIS18

---

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
c	LYS27-ASP52

---

site_id	PS00322
Number of Residues	7
Details	HISTONE_H3_1 Histone H3 signature 1. KAPRKQL

Chain	Residue	Details
A	LYS14-LEU20

---

site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
D	ARG89-GLY111

---

site_id	PS00959
Number of Residues	9
Details	HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI

Chain	Residue	Details
A	PRO66-ILE74

---

site_id	PS00973
Number of Residues	18
Details	USP_2 Ubiquitin specific protease (USP) domain signature 2. YeLiGIvsHkGtvne..GHY

Chain	Residue	Details
e	TYR411-TYR428

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P84228","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P84243","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Modified residue: {"description":"N6-glutaryllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"UniProtKB","id":"Q71DI3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	8
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	Modified residue: {"description":"N6-propionyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by PAK2","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	8
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	4
Details	Modified residue: {"description":"N6-glutaryllysine; alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"UniProtKB","id":"P62805","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	4
Details	Modified residue: {"description":"N6-(2-hydroxyisobutyryl)lysine; alternate","evidences":[{"source":"UniProtKB","id":"P0C0S8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	8
Details	Modified residue: {"description":"N6-(2-hydroxyisobutyryl)lysine","evidences":[{"source":"UniProtKB","id":"P0C0S8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P0C0S8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI22
Number of Residues	4
Details	Modified residue: {"description":"N5-methylglutamine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI23
Number of Residues	4
Details	Modified residue: {"description":"N6-glutaryllysine; alternate","evidences":[{"source":"UniProtKB","id":"P0C0S8","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI24
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI25
Number of Residues	4
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"source":"UniProtKB","id":"P62807","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI26
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"P0C1H4","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI27
Number of Residues	300
Details	Zinc finger: {"description":"UBP-type; degenerate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00502","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI28
Number of Residues	4
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PROSITE-ProRule","id":"PRU01035","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI29
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01035","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI30
Number of Residues	68
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3M99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MHS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FJC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6AQR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI31
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3M99","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI32
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FJC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI33
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4FIP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI34
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MHS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FJC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6AQR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI35
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MHS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FJC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6AQR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI36
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"22106047","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI37
Number of Residues	84
Details	Zinc finger: {"description":"SGF11-type","evidences":[{"source":"HAMAP-Rule","id":"MF_03047","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI38
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3M99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MHS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6AQR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI39
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4ZUX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI40
Number of Residues	300
Details	Domain: {"description":"Ubiquitin-like 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI41
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3M99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MHS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FIP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FJC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4FK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4W4U","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WA6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6AQR","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI42
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20395473","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20434206","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3M99","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZUX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---