4ZPR
Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA
Summary for 4ZPR
Entry DOI | 10.2210/pdb4zpr/pdb |
Related | 4ZP4 4ZPH 4ZPK |
Descriptor | Aryl hydrocarbon receptor nuclear translocator, Hypoxia-inducible factor 1-alpha, DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ... (4 entities in total) |
Functional Keywords | arnt, hif-1a, hre, bhlh-pas, protein transport-transcription-dna complex, protein transport/transcription/dna |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus: P53762 Cytoplasm : Q61221 |
Total number of polymer chains | 4 |
Total formula weight | 96229.26 |
Authors | Wu, D.,Potluri, N.,Lu, J.,Kim, Y.,Rastinejad, F. (deposition date: 2015-05-08, release date: 2015-08-12, Last modification date: 2023-09-27) |
Primary citation | Wu, D.,Potluri, N.,Lu, J.,Kim, Y.,Rastinejad, F. Structural integration in hypoxia-inducible factors. Nature, 524:303-308, 2015 Cited by PubMed: 26245371DOI: 10.1038/nature14883 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.902 Å) |
Structure validation
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