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4ZPR

Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AAryl hydrocarbon receptor nuclear translocatorpolymer38443437.41UniProt (P53762)
Pfam (PF00010)
Pfam (PF00989)
Pfam (PF14598)
In PDB
Mus musculus (Mouse)ARNT protein, Dioxin receptor, nuclear translocator, Hypoxia-inducible factor 1-beta, HIF1-beta
2BHypoxia-inducible factor 1-alphapolymer34539901.61UniProt (Q61221)
Pfam (PF00989)
Pfam (PF08447)
In PDB
Mus musculus (Mouse)HIF1-alpha, ARNT-interacting protein, Hypoxia inducible factor 1, alpha subunit
3CDNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3')polymer216527.21Mus musculus
4DDNA (5'-D(*CP*AP*CP*GP*AP*CP*CP*CP*GP*CP*AP*CP*GP*TP*AP*CP*GP*CP*AP*GP*C)-3')polymer216363.11Mus musculus
Sequence modifications
A: 82 - 464 (UniProt: P53762)
PDBExternal DatabaseDetails
Met 81-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight96229.3
All*Total formula weight96229.3
*Water molecules are not included.

225158

PDB entries from 2024-09-18

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