4ZDO
The crystal structure of T325S mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
Summary for 4ZDO
Entry DOI | 10.2210/pdb4zdo/pdb |
Related | 3HL2 4ZDL 4ZDP |
Descriptor | O-phosphoseryl-tRNA(Sec) selenium transferase, selenocysteine tRNA, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (5 entities in total) |
Functional Keywords | selenocysteine, trna, mutation, pyridoxal phosphate, transferase-rna complex, transferase/rna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 252429.78 |
Authors | French, R.L.,Simonovic, M. (deposition date: 2015-04-17, release date: 2016-04-20, Last modification date: 2023-09-27) |
Primary citation | Puppala, A.K.,French, R.L.,Matthies, D.,Baxa, U.,Subramaniam, S.,Simonovic, M. Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase. Sci Rep, 6:32563-32563, 2016 Cited by PubMed: 27576344DOI: 10.1038/srep32563 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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