4ZDO
The crystal structure of T325S mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | O-phosphoseryl-tRNA(Sec) selenium transferase | polymer | 501 | 55787.2 | 4 | UniProt (Q9HD40) Pfam (PF05889) | Homo sapiens (Human) | Liver-pancreas antigen,LP,SLA-p35,SLA/LP autoantigen,Selenocysteine synthase,Sec synthase,Selenocysteinyl-tRNA(Sec) synthase,Sep-tRNA:Sec-tRNA synthase,SepSecS,Soluble liver antigen,SLA,UGA suppressor tRNA-associated protein,tRNA(Ser/Sec)-associated antigenic protein |
| 2 | E (E) | selenocysteine tRNA | polymer | 87 | 27968.5 | 1 | GenBank (28372595) | Homo sapiens | |
| 3 | F, H, J, L (A, B, C, D) | (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE | non-polymer | 233.2 | 4 | Chemie (PLR) | |||
| 4 | G, I, K, M (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 5 | N, O, P, Q, R (A, B, C, D, E) | water | water | 18.0 | 469 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 501 (UniProt: Q9HD40)
| PDB | External Database | Details |
|---|---|---|
| Ser 325 | Thr 325 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 251117.3 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1312.5 | |
| All* | Total formula weight | 252429.8 |
