4ZDO

The crystal structure of T325S mutant of human SepSecS in complex with selenocysteine tRNA (tRNASec)

4ZDO の概要

• エントリーDOI: 10.2210/pdb4zdo/pdb
• 関連するPDBエントリー: 3HL2 4ZDL 4ZDP
• 分子名称: O-phosphoseryl-tRNA(Sec) selenium transferase, selenocysteine tRNA, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: selenocysteine, trna, mutation, pyridoxal phosphate, transferase-rna complex, transferase/rna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 252429.78

構造登録者

French, R.L.,Simonovic, M. (登録日: 2015-04-17, 公開日: 2016-04-20, 最終更新日: 2023-09-27)

• 主引用文献: Puppala, A.K.,French, R.L.,Matthies, D.,Baxa, U.,Subramaniam, S.,Simonovic, M.; Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.; Sci Rep, 6:32563-32563, 2016; PubMed: 27576344; DOI: 10.1038/srep32563

実験手法

X-RAY DIFFRACTION (2.65 Å)