4YUV

Crystal structure of Trypanosoma cruzi spermidine synthase in complex with decarboxylated S-adenosylmethionine

Summary for 4YUV

Entry DOI	10.2210/pdb4yuv/pdb
Related	4YUW 4YUX 4YUY 4YUZ 4YV0 4YV1 4YV2
Descriptor	Spermidine synthase, putative, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE (3 entities in total)
Functional Keywords	methyltransferase, polyamine, transferase
Biological source	Trypanosoma cruzi (strain CL Brener)
Total number of polymer chains	2
Total formula weight	68920.33
Authors	Amano, Y.,Tateishi, Y. (deposition date: 2015-03-19, release date: 2015-09-09, Last modification date: 2023-11-08)
Primary citation	Amano, Y.,Namatame, I.,Tateishi, Y.,Honboh, K.,Tanabe, E.,Niimi, T.,Sakashita, H. Structural insights into the novel inhibition mechanism of Trypanosoma cruzi spermidine synthase. Acta Crystallogr.,Sect.D, 71:1879-1889, 2015 Cited by PubMed: 26327378 DOI: 10.1107/S1399004715013048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation