4YV0
Crystal structure of Trypanosoma cruzi spermidine synthase in complex with (2S)-N-methyl-N-phenyl-2,3-dihydro-1,4-benzodioxine- 2-carboxamid
Summary for 4YV0
Entry DOI | 10.2210/pdb4yv0/pdb |
Related | 4YUV 4YUW 4YUX 4YUY 4YUZ 4YV1 4YV2 |
Descriptor | Spermidine synthase, putative, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, (2S)-N-methyl-N-phenyl-2,3-dihydro-1,4-benzodioxine-2-carboxamide, ... (4 entities in total) |
Functional Keywords | methyltransferase, polyamine synthesis, transferase |
Biological source | Trypanosoma cruzi (strain CL Brener) |
Total number of polymer chains | 4 |
Total formula weight | 138379.26 |
Authors | Amano, Y.,Tateishi, Y. (deposition date: 2015-03-19, release date: 2015-09-16, Last modification date: 2023-11-08) |
Primary citation | Amano, Y.,Namatame, I.,Tateishi, Y.,Honboh, K.,Tanabe, E.,Niimi, T.,Sakashita, H. Structural insights into the novel inhibition mechanism of Trypanosoma cruzi spermidine synthase Acta Crystallogr.,Sect.D, 71:1879-1889, 2015 Cited by PubMed: 26327378DOI: 10.1107/S1399004715013048 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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