4YV0

Crystal structure of Trypanosoma cruzi spermidine synthase in complex with (2S)-N-methyl-N-phenyl-2,3-dihydro-1,4-benzodioxine- 2-carboxamid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Spermidine synthase, putative	polymer	304	34103.7	4	UniProt (Q4DA73) Pfam (PF17284) Pfam (PF01564) In PDB	Trypanosoma cruzi (strain CL Brener)
2	A, B, C, D	5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE	non-polymer		356.4	4	Chemie (S4M)
3	B, D	(2S)-N-methyl-N-phenyl-2,3-dihydro-1,4-benzodioxine-2-carboxamide	non-polymer		269.3	2	Chemie (4JW)
4		water	water		18.0	276	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 296 (UniProt: Q4DA73)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	136414.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1964.4
All*	Total formula weight	138379.3

*Water molecules are not included.