4XM6
Anthrax toxin lethal factor with ligand-induced binding pocket
Summary for 4XM6
Entry DOI | 10.2210/pdb4xm6/pdb |
Related | 1YQY 4PKQ 4PKR 4PKS 4PKT 4PKU 4PKV 4PKW 4WF6 4XM7 4XM8 |
Descriptor | Lethal factor, N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-(2-methylpropyl)-D-valinamide, ZINC ION, ... (5 entities in total) |
Functional Keywords | anthrax toxin, lethal factor, metalloproteinase, metalloprotease, structural dynamics, ligand-induced conformational change, toxin, hydrolase |
Biological source | Bacillus anthracis |
Total number of polymer chains | 1 |
Total formula weight | 60986.04 |
Authors | Maize, K.M.,De la Mora-Rey, T.,Finzel, B.C. (deposition date: 2015-01-14, release date: 2015-11-11, Last modification date: 2023-09-27) |
Primary citation | Maize, K.M.,Kurbanov, E.K.,Johnson, R.L.,Amin, E.A.,Finzel, B.C. Ligand-induced expansion of the S1' site in the anthrax toxin lethal factor. Febs Lett., 589:3836-3841, 2015 Cited by PubMed: 26578066DOI: 10.1016/j.febslet.2015.11.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.352 Å) |
Structure validation
Download full validation report