4PKT
Anthrax toxin lethal factor with bound small molecule inhibitor 13
Summary for 4PKT
Entry DOI | 10.2210/pdb4pkt/pdb |
Related | 1J7N 1JKY 1PWP 1PWQ 1PWU 1PWV 1PWW 1YQY 1ZXV 4DV8 4PKQ 4PKR 4PKS 4PKU 4PKV 4PKW |
Descriptor | Lethal factor, N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-(4-nitrobenzyl)-D-alaninamide, ZINC ION, ... (4 entities in total) |
Functional Keywords | anthrax toxin, lethal factor, metalloproteinase, metalloprotease, structural dynamics, ligand-induced conformational change, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bacillus anthracis |
Total number of polymer chains | 1 |
Total formula weight | 60912.86 |
Authors | Maize, K.M.,De la Mora, T.,Finzel, B.C. (deposition date: 2014-05-15, release date: 2014-11-12, Last modification date: 2023-12-27) |
Primary citation | Maize, K.M.,Kurbanov, E.K.,De La Mora-Rey, T.,Geders, T.W.,Hwang, D.J.,Walters, M.A.,Johnson, R.L.,Amin, E.A.,Finzel, B.C. Anthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand binding. Acta Crystallogr.,Sect.D, 70:2813-2822, 2014 Cited by PubMed: 25372673DOI: 10.1107/S1399004714018161 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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