4PKT
Anthrax toxin lethal factor with bound small molecule inhibitor 13
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Lethal factor | polymer | 519 | 60436.0 | 1 | UniProt (P15917) Pfam (PF09156) Pfam (PF07737) In PDB | Bacillus anthracis | LF,Anthrax lethal toxin endopeptidase component |
| 2 | A | N~2~-[(4-fluoro-3-methylphenyl)sulfonyl]-N-hydroxy-N~2~-(4-nitrobenzyl)-D-alaninamide | non-polymer | 411.4 | 1 | Chemie (30O) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 265 - 776 (UniProt: P15917)
| PDB | External Database | Details |
|---|---|---|
| Ser 262 | - | expression tag |
| Asn 263 | - | expression tag |
| Ala 264 | - | expression tag |
| Ser 266 | Ala 299 | engineered mutation |
| Leu 777 | - | expression tag |
| Val 778 | - | expression tag |
| Pro 779 | - | expression tag |
| Arg 780 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60436.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 476.8 | |
| All* | Total formula weight | 60912.9 |
