4X42

Crystal structure of DEN4 ED3 mutant with epitope two residues substituted from DEN3 ED3

Summary for 4X42

• Entry DOI: 10.2210/pdb4x42/pdb
• Related: 3WE1
• Descriptor: Envelope protein E, SULFATE ION (3 entities in total)
• Functional Keywords: sero-specificity, epitope graft mutants, elisa, structural protein, immune system
• Biological source: Dengue virus type 4 (DENV-4)
• Total number of polymer chains: 6
• Total formula weight: 69529.45

Authors

Kulkarni, M.R.,Islam, M.M.,Numoto, N.,Elahi, M.M.,Ito, N.,Kuroda, Y. (deposition date: 2014-12-02, release date: 2015-09-09, Last modification date: 2023-11-08)

• Primary citation: Kulkarni, M.R.,Islam, M.M.,Numoto, N.,Elahi, M.,Mahib, M.R.,Ito, N.,Kuroda, Y.; Structural and biophysical analysis of sero-specific immune responses using epitope grafted Dengue ED3 mutants.; Biochim.Biophys.Acta, 1854:1438-1443, 2015; PubMed: 26160751; DOI: 10.1016/j.bbapap.2015.07.004

Experimental method

X-RAY DIFFRACTION (2.78 Å)