3WE1

Crystal structure of Dengue 4 Envelope protein domain III (ED3)

Summary for 3WE1

• Entry DOI: 10.2210/pdb3we1/pdb
• Descriptor: Envelope protein E (2 entities in total)
• Functional Keywords: immunoglobulin like domain, cell surface receptor binding, represent epitope, virus surface, structural protein, immune system
• Biological source: Dengue virus type 4 (DENV-4)
• Cellular location: Capsid protein C: Virion . Peptide pr: Secreted . Small envelope protein M: Virion membrane ; Multi-pass membrane protein . Envelope protein E: Virion membrane ; Multi-pass membrane protein . Non-structural protein 1: Secreted . Non-structural protein 2A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Serine protease subunit NS2B: Host endoplasmic reticulum membrane; Multi-pass membrane protein . Serine protease NS3: Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Non-structural protein 4A: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . Non-structural protein 4B: Host endoplasmic reticulum membrane ; Multi-pass membrane protein . RNA-directed RNA polymerase NS5: Host endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side: P09866
• Total number of polymer chains: 2
• Total formula weight: 22954.16

Authors

Elahi, M.,Islam, M.M.,Noguchi, K.,Yohda, M.,Toh, H.,Kuroda, Y. (deposition date: 2013-06-27, release date: 2014-01-22, Last modification date: 2023-11-08)

• Primary citation: Elahi, M.,Islam, M.M.,Noguchi, K.,Yohda, M.,Toh, H.,Kuroda, Y.; Computational prediction and experimental characterization of a "size switch type repacking" during the evolution of dengue envelope protein domain III (ED3).; Biochim.Biophys.Acta, 1844:585-592, 2014; PubMed: 24373879; DOI: 10.1016/j.bbapap.2013.12.013

Experimental method

X-RAY DIFFRACTION (2.278 Å)