4X42
Crystal structure of DEN4 ED3 mutant with epitope two residues substituted from DEN3 ED3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Envelope protein E | polymer | 107 | 11524.2 | 6 | UniProt (P09866) Pfam (PF02832) | Dengue virus type 4 (DENV-4) | |
| 2 | G, H, I, J (A, B, C) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 575 - 679 (UniProt: P09866)
| PDB | External Database | Details |
|---|---|---|
| Gly 573 | - | expression tag |
| Ser 574 | - | expression tag |
| Asp 663 | Asn 663 | engineered mutation |
| Lys 664 | Ser 664 | engineered mutation |
| Lys 667 | Thr 667 | engineered mutation |
| Asn 669 | His 669 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 69145.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 384.3 | |
| All* | Total formula weight | 69529.4 |
