4X42

Crystal structure of DEN4 ED3 mutant with epitope two residues substituted from DEN3 ED3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Envelope protein E	polymer	107	11524.2	6	UniProt (P09866) Pfam (PF02832)	Dengue virus type 4 (DENV-4)
2	G, H, I, J (A, B, C)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	11	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 575 - 679 (UniProt: P09866)

PDB	External Database	Details
Gly 573	-	expression tag
Ser 574	-	expression tag
Asp 663	Asn 663	engineered mutation
Lys 664	Ser 664	engineered mutation
Lys 667	Thr 667	engineered mutation
Asn 669	His 669	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	69145.2
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	69529.4

*Water molecules are not included.