4WXS
Crystal Structure of the E396D SNP Variant of the Myocilin Olfactomedin Domain
Summary for 4WXS
Entry DOI | 10.2210/pdb4wxs/pdb |
Related | 4WXQ 4wxu |
Descriptor | Myocilin, CALCIUM ION, GLYCEROL, ... (7 entities in total) |
Functional Keywords | beta propeller, 5 bladed propeller, olfactomedin, protein binding |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted. Myocilin, C-terminal fragment: Secreted. Myocilin, N-terminal fragment: Endoplasmic reticulum: Q99972 |
Total number of polymer chains | 1 |
Total formula weight | 31998.86 |
Authors | |
Primary citation | Donegan, R.K.,Hill, S.E.,Freeman, D.M.,Nguyen, E.,Orwig, S.D.,Turnage, K.C.,Lieberman, R.L. Structural basis for misfolding in myocilin-associated glaucoma. Hum.Mol.Genet., 24:2111-2124, 2015 Cited by PubMed: 25524706DOI: 10.1093/hmg/ddu730 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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