4WXS

Crystal Structure of the E396D SNP Variant of the Myocilin Olfactomedin Domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001952	biological_process	regulation of cell-matrix adhesion
A	0005615	cellular_component	extracellular space
A	0030335	biological_process	positive regulation of cell migration
A	0051492	biological_process	regulation of stress fiber assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue CA A 601

Chain	Residue
A	ASP380
A	ASN428
A	ALA429
A	ILE477
A	ASP478
A	HOH833
A	HOH836

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site_id	AC2
Number of Residues	10
Details	binding site for residue GOL A 602

Chain	Residue
A	SER444
A	ASN469
A	LYS472
A	TYR473
A	SER474
A	HOH944
A	HOH948
A	HOH963
A	TRP373
A	SER441

---

site_id	AC3
Number of Residues	11
Details	binding site for residue GOL A 603

Chain	Residue
A	MET271
A	ARG272
A	PRO274
A	VAL328
A	VAL329
A	ASP478
A	ASN480
A	PHE487
A	HOH898
A	HOH899
A	HOH959

---

site_id	AC4
Number of Residues	7
Details	binding site for residue GOL A 604

Chain	Residue
A	LYS314
A	VAL315
A	HIS316
A	ILE317
A	GLU352
A	TYR442
A	HOH848

---

site_id	AC5
Number of Residues	7
Details	binding site for residue PG4 A 605

Chain	Residue
A	TRP250
A	SER372
A	GLN424
A	LYS500
A	HOH733
A	HOH742
A	HOH791

---

site_id	AC6
Number of Residues	7
Details	binding site for residue P6G A 606

Chain	Residue
A	PRO274
A	LYS275
A	TYR330
A	ASP384
A	GLU385
A	PRO481
A	HOH970

---

site_id	AC7
Number of Residues	5
Details	binding site for residue NA A 607

Chain	Residue
A	GLY326
A	ASP380
A	LEU381
A	ASP478
A	HOH832

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PDB","id":"4WXQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WXS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WXU","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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