4WXS
Crystal Structure of the E396D SNP Variant of the Myocilin Olfactomedin Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Myocilin | polymer | 277 | 31183.0 | 1 | UniProt (Q99972) Pfam (PF02191) | Homo sapiens (Human) | Myocilin 55 kDa subunit,Trabecular meshwork-induced glucocorticoid response protein |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C, D, E (A) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | F (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | G (A) | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
| 6 | H (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | I (A) | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A: 228 - 504 (UniProt: Q99972)
| PDB | External Database | Details |
|---|---|---|
| Asp 396 | Glu 396 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31183.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 815.9 | |
| All* | Total formula weight | 31998.9 |
