4WXS
Crystal Structure of the E396D SNP Variant of the Myocilin Olfactomedin Domain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Myocilin | polymer | 277 | 31183.0 | 1 | UniProt (Q99972) Pfam (PF02191) In PDB | Homo sapiens (Human) | Myocilin 55 kDa subunit,Trabecular meshwork-induced glucocorticoid response protein |
2 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
5 | A | HEXAETHYLENE GLYCOL | non-polymer | 282.3 | 1 | Chemie (P6G) | |||
6 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
7 | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence modifications
A: 228 - 504 (UniProt: Q99972)
PDB | External Database | Details |
---|---|---|
Asp 396 | Glu 396 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 31183.0 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 815.9 | |
All* | Total formula weight | 31998.9 |