4WXQ
Crystal Structure of the Myocilin Olfactomedin Domain
Summary for 4WXQ
Entry DOI | 10.2210/pdb4wxq/pdb |
Related | 4WXS 4WXU |
Descriptor | Myocilin, CALCIUM ION, HEXAETHYLENE GLYCOL, ... (5 entities in total) |
Functional Keywords | beta propeller, 5 bladed propeller, olfactomedin, protein binding |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted . Myocilin, C-terminal fragment: Secreted. Myocilin, N-terminal fragment: Endoplasmic reticulum: Q99972 |
Total number of polymer chains | 1 |
Total formula weight | 33236.36 |
Authors | Orwig, S.D.,Turnage, K.C.,Donegan, R.K.,Lieberman, R.L. (deposition date: 2014-11-14, release date: 2015-04-01, Last modification date: 2017-09-06) |
Primary citation | Donegan, R.K.,Hill, S.E.,Freeman, D.M.,Nguyen, E.,Orwig, S.D.,Turnage, K.C.,Lieberman, R.L. Structural basis for misfolding in myocilin-associated glaucoma. Hum.Mol.Genet., 24:2111-2124, 2015 Cited by PubMed: 25524706DOI: 10.1093/hmg/ddu730 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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