4UEE
Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Ala-Y(PO2CH2)-homoPhe-OH
Summary for 4UEE
Entry DOI | 10.2210/pdb4uee/pdb |
Related | 4UEF 4UEZ 4UF4 5AEK |
Descriptor | CARBOXYPEPTIDASE A1, (2S)-2-{[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, ZINC ION, ... (4 entities in total) |
Functional Keywords | hydrolase, cpa1, phosphinic inhibitor |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P15085 |
Total number of polymer chains | 2 |
Total formula weight | 70421.44 |
Authors | Gallego, P.,Covaleda, G.,Costenaro, L.,Devel, L.,Dive, V.,Aviles, F.X.,Reverter, D. (deposition date: 2014-12-17, release date: 2016-01-20, Last modification date: 2024-10-23) |
Primary citation | Gallego, P.,Covaleda, G.,Devel, L.,Dive, V.,Aviles, F.X.,Reverter, D. Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors To be Published, |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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