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4UEE

Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Ala-Y(PO2CH2)-homoPhe-OH

Summary for 4UEE
Entry DOI10.2210/pdb4uee/pdb
Related4UEF 4UEZ 4UF4 5AEK
DescriptorCARBOXYPEPTIDASE A1, (2S)-2-{[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, ZINC ION, ... (4 entities in total)
Functional Keywordshydrolase, cpa1, phosphinic inhibitor
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted: P15085
Total number of polymer chains2
Total formula weight70421.44
Authors
Gallego, P.,Covaleda, G.,Costenaro, L.,Devel, L.,Dive, V.,Aviles, F.X.,Reverter, D. (deposition date: 2014-12-17, release date: 2016-01-20, Last modification date: 2024-10-23)
Primary citationGallego, P.,Covaleda, G.,Devel, L.,Dive, V.,Aviles, F.X.,Reverter, D.
Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors
To be Published,
Experimental method
X-RAY DIFFRACTION (2.27 Å)
Structure validation

227561

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