4UEZ
Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH
Summary for 4UEZ
Entry DOI | 10.2210/pdb4uez/pdb |
Related | 4UEE 4UEF 4UF4 5AEK |
Descriptor | HUMAN CARBOXYPEPTIDASE A1, ZINC ION, (2S)-3-[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]-2-phenylethyl}(hydroxy)phosphoryl]-2-benzylpropanoic acid, ... (4 entities in total) |
Functional Keywords | hydrolase, carboxypeptidase, cpa1, phosphinic inhibitor |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P15085 |
Total number of polymer chains | 2 |
Total formula weight | 70545.58 |
Authors | Gallego, P.,Covaleda, G.,Costenaro, L.,Devel, L.,Dive, V.,Aviles, F.X.,Reverter, D. (deposition date: 2014-12-22, release date: 2016-01-20, Last modification date: 2023-12-20) |
Primary citation | Gallego, P.,Covaleda, G.,Devel, L.,Dive, V.,Aviles, F.X.,Reverter, D. Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors To be Published, |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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