4UEE

Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Ala-Y(PO2CH2)-homoPhe-OH

Summary for 4UEE

• Entry DOI: 10.2210/pdb4uee/pdb
• Related: 4UEF 4UEZ 4UF4 5AEK
• Descriptor: CARBOXYPEPTIDASE A1, (2S)-2-{[(R)-{(1R)-1-[(N-acetyl-L-leucyl)amino]ethyl}(hydroxy)phosphoryl]methyl}-4-phenylbutanoic acid, ZINC ION, ... (4 entities in total)
• Functional Keywords: hydrolase, cpa1, phosphinic inhibitor
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: P15085
• Total number of polymer chains: 2
• Total formula weight: 70421.44

Authors

Gallego, P.,Covaleda, G.,Costenaro, L.,Devel, L.,Dive, V.,Aviles, F.X.,Reverter, D. (deposition date: 2014-12-17, release date: 2016-01-20, Last modification date: 2023-12-20)

• Primary citation: Gallego, P.,Covaleda, G.,Devel, L.,Dive, V.,Aviles, F.X.,Reverter, D.; Crystal Structure of the Human Carboxypeptidase A1 in Complex with Phosphinic Inhibitors; To be Published,

Experimental method