4UAW
DNA polymerase beta substrate complex with a templating adenine and incoming 8-oxodGTP, 0 s
Summary for 4UAW
Entry DOI | 10.2210/pdb4uaw/pdb |
Related | 4UAY 4UAZ 4UB1 4UB2 4UB3 4UB4 4UB5 4UBB 4UBC |
Descriptor | 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... (8 entities in total) |
Functional Keywords | dna polymerase, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48341.19 |
Authors | Freudenthal, B.D.,Wilson, S.H.,Beard, W.A. (deposition date: 2014-08-11, release date: 2014-11-12, Last modification date: 2023-12-27) |
Primary citation | Freudenthal, B.D.,Beard, W.A.,Perera, L.,Shock, D.D.,Kim, T.,Schlick, T.,Wilson, S.H. Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517:635-639, 2015 Cited by PubMed: 25409153DOI: 10.1038/nature13886 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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